Associate Professor Philip Giffard presents ‘Microbial genotyping based on resolution optimised sets of polymorphisms and high resolution melt analysis’, on 15 October at the special time of 1.30pm.
Microbial genotyping is central to clinical microbiology, infection control, public health microbiology, food microbiology, environmental microbiology and biodefense. Perhaps the only constant in the field of microbial genotyping is continuous invention and innovation.
The microbial genotyping group at Queensland University of Technology has postulated that genotyping methods can best be designed by using computer-aided bioinformatic analyses to derive resolution-optimised sets of genetic markers from large databases of comparative genetic information. In this way, the genotyping method used is a function of the question being asked, and the marker sets efficiently provide the required genotyping information. This approach has now been implemented.
The 'Minimum SNPs’ software package has been constructed and used in the development of SNP and binary marker-based genotyping methods for major bacterial pathogens. The technology platform is real-time PCR, with high resolution melt analysis recently showing particular promise for high throughput applications.
Associate Professor Philip Giffard is with the Institute of Health and Biomedical Innovation, and School of Life Sciences, Queensland University of Technology.
This seminar takes place in Seminar Room, Menzies School of Health Research, Building 58, Royal Darwin Hospital Campus.